Bupropion (generic for Wellbutrin®)

Everyone faces emotional challenges in life. It’s not easy, but you are not alone. Medication isn’t for everyone, but it can be life-changing for those who need it. Consult with a psychiatry provider to help you determine whether a medication like bupropion could be right for you and help you feel your best again.

FDA-approved for depression

Prescribed by licensed psychiatry providers, if appropriate

Non-controlled medication, no addictive properties

Medication Bottle (2)

Bupropion Overview

How it works

Bupropion is in a class of medication called dopamine reuptake inhibitors. It is used to treat depression, attention deficit hyperactivity disorder, and help people stop smoking. Bupropion works by increasing the amount of norepinephrine and dopamine, natural substances in the brain that help maintain mental balance.


Bupropion is a non-controlled medication, which means that it is not classified as having euphoric or addictive properties. There are no cravings, no hazardous behaviors, and no examples of prolonged addictive behavior associated with it.

Talk to your doctor about the safe use of alcoholic beverages while you are taking bupropion. Alcohol can make the side effects of bupropion worse.

How it should be used

It may take 2 to 4 weeks or longer before you feel the full benefit of bupropion. Continue to take bupropion even if you feel well. 

Do not stop taking bupropion without talking to your doctor. If you suddenly stop taking bupropion, you may experience withdrawal symptoms. Your doctor will probably decrease your dose gradually.

What to do if you forget a dose

Skip the missed dose and continue your regular dosing schedule. Always allow the full scheduled amount of time to pass between doses of bupropion. Do not take a double dose to make up for a missed one.

Side effects

Bupropion may cause side effects. However, they tend to go away after an adaptation period. Tell your doctor if any of these symptoms are severe or do not go away:

  •     drowsiness
  •     anxiety
  •     excitement
  •     difficulty falling asleep or staying asleep
  •     dry mouth
  •     dizziness
  •     headache
  •     nausea
  •     vomiting
  •     stomach pain
  •     uncontrollable shaking of a part of the body
  •     loss of appetite
  •     weight loss
  •     constipation
  •     excessive sweating
  •     ringing in the ears
  •     changes in your sense of taste
  •     frequent urination
  •     sore throat

Some side effects can be serious. If you experience either of the following symptoms or those listed in the IMPORTANT WARNING or SPECIAL PRECAUTIONS sections, call your doctor immediately:

  •     seizures
  •     confusion
  •     hallucinating (seeing things or hearing voices that do not exist)
  •     irrational fears
  •     muscle or joint pain
  •     rapid, pounding, or irregular heartbeat

Bupropion may cause an increase in your blood pressure. Your doctor may check your blood pressure before starting treatment and regularly while you are taking this medication, especially if you also are using nicotine replacement therapy.

Bupropion may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

In case of emergency or overdose

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can’t be awakened, immediately call emergency services at 911.


The information about this medication is not intended to replace medical counseling. Please consult your pharmacist and/or health provider for more comprehensive information. You can also find the Medication Guide containing the manufacturer’s patient information approved by the FDA here.

Information Source


Last Revised on 02/15/2018