Trazodone (generic for Desyrel®)

Everyone faces emotional challenges in life. It’s not easy, but you are not alone. Medication isn’t for everyone, but it can be life-changing for those who need it. Consult with a psychiatry provider to help you determine whether a medication like trazodone could be right for you and help you feel your best again.

FDA-approved for depression and anxiety

Prescribed by licensed psychiatry providers, if appropriate

Non-controlled medication, no addictive properties

Medication Bottle (2)

Trazodone Overview

How it works

Trazodone is in a class of medication called serotonin modulators. It is used to treat depression, anxiety, insomnia, and other conditions. Trazodone works by increasing the amount of serotonin, a natural substance in the brain that helps maintain mental balance.


Safety

Trazodone is a non-controlled medication, which means that it is not classified as having euphoric or addictive properties. There are no cravings, no hazardous behaviors, and no examples of prolonged addictive behavior associated with it.

Trazodone may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.

Do not drive a car or operate machinery until you know how this medication affects you. Remember that alcohol can add to the drowsiness caused by this medication.


How it should be used

It may take 2 to 4 weeks or longer before you feel the full benefit of trazodone. Continue to take trazodone even if you feel well. 

Do not stop taking trazodone without talking to your doctor. If you suddenly stop taking trazodone, you may experience withdrawal symptoms such as anxiety, agitation, or difficulty falling asleep or staying asleep. Your doctor will probably decrease your dose gradually.


What to do if you forget a dose

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.


Side effects

Trazodone may cause side effects. However, they tend to go away after an adaptation period. Tell your doctor if any of these symptoms are severe or do not go away:

  • headache
  • nausea
  • vomiting
  • bad taste in mouth
  • diarrhea
  • constipation
  • changes in appetite or weight
  • weakness or tiredness
  • nervousness
  • dizziness or lightheadedness
  • feeling unsteady when walking
  • decreased ability to concentrate or remember things
  • confusion
  • nightmares
  • muscle pain
  • dry mouth
  • rash
  • sweating
  • changes in sexual desire or ability
  • uncontrollable shaking of a part of the body
  • numbness, burning, or tingling in the arms, legs, hands, or feet
  • decreased coordination
  • tired, red, or itchy eyes
  • ringing in ears

Some side effects can be serious. If you experience either of the following symptoms or those listed in the IMPORTANT WARNING or SPECIAL PRECAUTIONS sections, call your doctor immediately:

  • chest pain
  • fast, pounding, or irregular heartbeat
  • loss of consciousness (coma)
  • fainting
  • seizures
  • shortness of breath
  • unusual bruising or bleeding
  • painful, long lasting erections in males

Trazodone may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.


In case of emergency or overdose

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can’t be awakened, immediately call emergency services at 911.


Disclaimer

The information about this medication is not intended to replace medical counseling. Please consult your pharmacist and/or health provider for more comprehensive information. You can also find the Medication Guide containing the manufacturer’s patient information approved by the FDA here.


Information Source

MedlinePlus

Last Revised on 04/15/2017